Effect of Bisphenol A Level In Serum and Follicular Fluid On ICSI OutCome


  • Sarah Hamza High Institute of Infertility Diagnosis and Assisted Reproductive Technologies, Al Nahrain University, Baghdad, Iraq
  • Muayad Abbood High Institute of Infertility Diagnosis and Assisted Reproductive Technologies, Al Nahrain University, Baghdad, Iraq.
  • Mufeda Jwad High Institute of Infertility Diagnosis and Assisted Reproductive Technologies, Al Nahrain University, Baghdad, Iraq.




Bisphenol A (BPA), Infertility, ICSI


Infertility is the disability of a couple to obtain pregnancy after one year of
sexual intercourse that is unprotected and regular. Bisphenol A is an industrial
chemical spread worldwide, that is a raw material utilized in multiple
industries. Bisphenol A is assorted as an endocrine-disrupting chemical,
which can interfere with hormone activity. This study aimed to assess the
effect of BPA levels in serum on ICSI outcomes. The study was conducted at
the High Institute for Infertility Diagnosis and Assisted Reproductive
Technologies / Al-Nahrain University during the period from October 2021
to April 2022. sixty infertile women enrolled in this study. BPA levels were
analyzed through an enzyme-linked immunosorbent assay (ELISA)
technique. Mean serum BPA was not significantly higher in non-pregnant
women in comparison with that of pregnant women. Serum BPA was
positively correlated to immature oocytes (MI) and abnormal oocytes. Also,
BPA inversely correlated to Grade1 embryos and positively correlated to
Grade 3 embryos. Bisphenol A can be detected in sera of infertile female
undergoing ICSI. High BPA level in serum may impact oocyte quality and
embryo grading


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How to Cite

Hamza S, Abbood M, Jwad M. Effect of Bisphenol A Level In Serum and Follicular Fluid On ICSI OutCome. IJEIR [Internet]. 2022 Jun. 8 [cited 2023 Nov. 29];12(1):1-15. Available from: https://ijeir.net/index.php/ijeir/article/view/79



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