The correlation of intratesticular testosterone with body mass  index and smoking

Sara Alkubaisy; Ali Ibrahim Rahim; Ula Alkawaz

doi:10.28969/IJEIR.v13.i2.r2.23

Authors

Sara Alkubaisy High Institute for Infertility Diagnosis and Assisted Reproductive Technology, Al-Nahrain University. Baghdad, Iraq,
Ali Ibrahim Rahim College of Medicine, Al-Ameed University https://orcid.org/0000-0003-4409-2050
Ula alkawaz High Institute for Infertility Diagnosis and Assisted Reproductive Technology, Al-Nahrain University. Baghdad, Iraq,

DOI:

https://doi.org/10.28969/IJEIR.v13.i2.r2.23

Keywords:

Intratesticular testosterone, 17 hydroxyprogesterone, TESE, BMI, Smoking

Abstract

Intratesticular testosterone plays a crucial role in male reproductive
function and overall health. Body Mass Index (BMI) and smoking are known
lifestyle factors that can influence hormonal balances. Elevated BMI has been
associated with alterations in testosterone levels, impacting male fertility and
endocrine function. The aim was to examine the concurrent relationships
between intratesticular testosterone, BMI, and smoking habits. Biopsies of the
testicles were taken from 32 patients with non-obstructive azoospermia.
Testicular sperm extraction (TESE) under spinal or general anesthesia was
performed after a comprehensive history, physical examination, and
investigations. After performing a minced biopsy and centrifuging the fluid,
testicular fluid was extracted. The highest intratesticular testosterone levels
were in normal patients and lowest levels in over weight patient; on the
contrary the highest serum 17-hydroxyprogesterone levels were found in over
weight patient and lowest levels in normal weight patients; There were
insignificantly higher both intratesticular testosterone and 17-
hydroxyprogesterone levels in non-smokers. In conclusion, the statistical
analysis revealed that there is an insignificantly low correlation between
intratesticular testosterone levels, BMI, and smoking.

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